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Lanthionine Bridged Peptides

This product line has been selected to become very important for the portfolio of Lotus Apothecary Project Alleviate. Patents and patent applications shall be transmitted to the company by the patent owner and LLC -shareholder, Dr. Winfried Kolbeck. The idea and invention came from Murray Goodman, professor and leader of the Institute of Organic Chemistry at the University of California, San Diego (UCSD), USA. He and his scientific group showed impressively that in many cases the concept to substitute natural disulfide bridges by Lanthionine bridges is enhancing the stability and efficacy of selected peptides significantly.

The top product of this line is a lantionine bridged encephaline (a body's own factor to regulate pain) has shown remarkable higher efficacy in pre-clinical experiments in comparison with morphine (and encephaline). The bulk active pharmaceutical ingredient (API) has to be manufactured under GMP conditions, as well, to be allowed for use in clinical studies. The objective of Lotus Apothecary Project Alleviate is to have synthesized this substance at competent companies. Lotus Apothecary Project Alleviate has access to under GMP conditions. Later, the formulation for clinical application shall be done in Lotus Apothecary Project Alleviate's plant. A special aspect for this product is given due to a possibly combined application with the pox virus preparation in the treatment of heavy tumor pains for example. The pox virus preparations alone have already shown amazing results in pain treatment of cancer patients. Combined with the increased efficacy and specialty of the Encephaline derivative, it might be possible to offer a significantly improved pain management, and to achieve human dignity for cancer patients - especially in their final stadium (hospice).


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Lotus Apothecary Project Alleviate; Head office (NV), Administration office (NV)